Percentage of the instruments used for the therapeutic drug monitoring proficiency testing during 2015–2019
| Name of instrument | Year | ||||
|---|---|---|---|---|---|
| 2015 | 2016 | 2017 | 2018 | 2019 | |
| Abbott Architect i System | 46.4 | 49.2 | 46.9 | 47.4 | 45.1 |
| Roche Cobas c311/c501/c502/c702 | 6.0 | - | 5.0 | 11.8 | 17.2 |
| LC-MS/MS | 1.8 | 4.3 | 6.7 | 8.2 | 10.1 |
| Roche Cobas Integra | 18.0 | 18.6 | 16.9 | 11.1 | 5.7 |
| Siemens Dimension | 3.7 | 2.9 | 3.7 | 4.2 | 5.4 |
| Roche Cobas E170/e411/e601/e602/e801 | - | 4.5 | 4.3 | 4.4 | 4.0 |
| Siemens ADVIA Centaur | 3.2 | 3.9 | 4.2 | 4.0 | 3.4 |
| Beckman Olympus AU Series | 1.0 | 1.6 | 1.4 | 1.4 | 1.6 |
| Ortho Vitros5600 | - | 0.2 | - | - | 1.1 |
| Roche AVL9180 | - | 0.3 | 0.7 | 0.8 | 1.0 |
| Nova 4 Analyzer | - | - | 0.6 | 0.7 | 0.9 |
| Roche/Hitachi Systems | 3.8 | 1.2 | 0.9 | 0.7 | 0.7 |
| Toshiba Chemistry Analyzer | 1.2 | 0.7 | 0.3 | 0.3 | 0.7 |
| Roche 9100 Series (ISE mode) | 0.2 | 0.8 | 0.7 | 0.7 | 0.5 |
| ICP-MS | 0.1 | 0.2 | 0.2 | 0.2 | 0.2 |
| Hitachi AP720 | - | - | 0.9 | 0.2 | 0.2 |
| Atomic Absorption Spectrometers | 0.3 | 0.4 | 0.2 | 0.2 | 0.2 |
| Radioimmunoassay | 0.3 | 0.2 | 0.2 | 0.2 | 0.2 |
| Siemens Viva-E | 2.2 | 1.1 | 1.0 | 0.2 | 0.2 |
| Beckman UniCel DxI800 | - | 1.1 | 0.2 | 0.2 | 0.1 |
| Siemens Vista | 0.7 | 0.5 | 0.3 | 0.2 | 0.1 |
| Siemens Atellica CH 930 Analyzer | - | - | - | - | 0.1 |
| GC-MS | - | - | - | 0.1 | - |
| Beckman UniCel DxC Synchron | 3.3 | 1.7 | 0.2 | - | - |
| Others | 7.8 | 6.7 | 4.7 | 3.2 | 1.6 |
| Total | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
Values are presented as %. The instruments were from the following companies: Abbott Laboratories (Chicago, IL, USA), Roche Diagnostics (Mannheim, Germany), Siemens (Erlangen, Germany), Beckman Coulter Inc. (Brea, CA, USA), Ortho Clinical Diagnostics (Raritan, NJ, USA), Nova Biomedical Corp. (Waltham, MA, USA), Toshiba Medical Systems (Tokyo, Japan), and Hitachi High-Technologies Corp. (Tokyo, Japan). Instruments of the same series are combined, and some minor instruments with various manufacturers are substituted as their methods: liquid chromatography-tandem mass spectrometry (LC-MS/MS), inductively coupled plasma-mass spectrometry (ICP-MS), radioimmunoassay, gas chromatography–mass spectrometry (GC-MS), and atomic absorption spectrometry.