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Design and Laboratory Implementation of Web Application for Collaboratively Setting Reference Intervals
J Lab Med Qual Assur 2019;41:166-171
Published online September 30, 2019
© 2019 Korean Association of External Quality Assessment Service.

Byung Ryul Jeon and Yong-Wha Lee

Department of Laboratory Medicine & Genetics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
Correspondence to: Yong-Wha Lee
Department of Laboratory Medicine and Genetics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, 170 Jomaruro, Wonmi-gu, Bucheon 14584, Korea
Tel: +82-32-621-5943 Fax: +82-32-621-5944 E-mail: lywmd@schmc.ac.kr
Received March 5, 2019; Revised May 27, 2019; Accepted June 11, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract

Background:

Although the same equipment and reagents can be employed for inspecting identical samples, the setting and verification methods for the corresponding reference intervals differ from each other, and such methods are not well established. To address the issues associated with establishing and validating reference intervals, a Web-based application is proposed for collaboratively setting reference intervals.

Methods:

A Web application was designed for automatically providing the statistical results associated with a reference interval upon receiving the corresponding test results from participating institutions and incorporating the cumulative data.

Results:

By employing the proposed Web-based application (www.referencerange.org), reference intervals can be collaboratively set based on objective and statistical analyses incorporating clinical chemistry results obtained from Korea Healthcare Association in the years 2016 and 2017. Cumulative data obtained from the existing input peer group associated with an inspection are updated in real time, and the current set reference interval is displayed in real time.

Conclusions:

In this study, a Web-based application is designed for collaboratively setting reference intervals whereby all Korean laboratories can easily participate, collectively set reference intervals, and apply the set reference intervals. Hence, the proposed application can aid in providing basic data associated with health information.

Keywords : Reference interval, Web-based application, Laboratory test
꽌濡

솚옄쓽 吏꾨떒쓽븰寃궗 寃곌낵뒗 李멸퀬援ш컙怨 븿猿 蹂닿퀬릺硫 李멸퀬援ш컙쓣 諛뷀깢쑝濡 븳 寃궗寃곌낵쓽 뙋젙 쓽븰쟻 쓽궗 寃곗젙뿉 留ㅼ슦 以묒슂븳 쁺뼢쓣 誘몄튇떎. 깉濡쒖슫 寃궗瑜 룄엯븯嫄곕굹 寃궗踰 蹂寃 떆 李멸퀬援ш컙쓽 젙솗븳 꽕젙 諛 쟻젅븳 寃利앹씠 슂援щ릺굹[1-5], 吏꾨떒쓽븰寃궗떎留덈떎 李멸퀬援ш컙 꽕젙怨 寃利앸갑踰뺤씠 꽌濡 떎瑜 肉먮쭔 븘땲씪 몴以솕릺뼱 엳吏 븡怨 二쇨쟻씠뼱꽌 씪遺 寃궗떎뿉꽌 씪遺 빆紐⑹뿉 빐 李멸퀬援ш컙씠 떎젣 옒紐 꽕젙릺怨 寃利앸맂 긽깭濡 쟻슜릺뼱 궗슜릺怨 엳떎.

떎젣濡 룞씪 빆紐⑹뿉 빐 룞씪 옣鍮꾩 떆빟쓣 궗슜븯뒗 寃쎌슦씪 븯뜑씪룄 李멸퀬援ш컙 꽕젙怨 寃利앸갑踰뺤씠 젣媛곴린 떎瑜닿퀬 젙由쎈릺뼱 엳吏 븡 떎젙씠떎. 씠뿉 蹂 뿰援ъ뿉꽌뒗 떎젣 寃궗떎뿉꽌 씠긽쟻쑝濡 쟻슜븷 닔 엳뒗 쟻젅븳 李멸퀬援ш컙 꽕젙諛⑸쾿쓣 젣떆븯怨 寃궗떎뿉꽌 돺寃 솢슜븷 닔 엳룄濡 븯怨좎옄 븯떎. 삉븳 李멸퀬援ш컙 꽕젙뿉 엳뼱꽌 옣븷슂씤쑝濡 뿬寃⑥뒗 異⑸텇븳 닔쓽 嫄닿컯씤 뜲씠꽣 솗蹂 臾몄젣 李멸퀬援ш컙 꽕젙뿉 븘슂븳 넻怨꾨텇꽍쓽 쟻슜뿉 븳 臾몄젣瑜 洹쇰낯쟻쑝濡 빐寃고븷 닔 엳뒗 쎒 湲곕컲 봽濡쒓렇옩쓣 援ъ텞븯怨좎옄 븯떎.

寃궗떎뿉꽌 떆뻾릺뒗 媛쒕퀎 寃궗뱾뿉 빐 씪씪씠 룆由쎌쟻씤 李멸퀬援ш컙 꽕젙쓣 븯뒗 寃껋 遺덇뒫븷 寃껋쑝濡 삁痢〓맖뿉 뵲씪 룞씪븳 옣鍮꾩 떆빟쓣 궗슜븯뒗 寃궗떎 媛꾩쓽 쎒 꽕듃썙궧쓣 넻빐 뜲씠꽣瑜 엯젰븯怨 李멸퀬援ш컙 꽕젙 넻怨꾨텇꽍 寃곌낵瑜 李몄뿬湲곌씠 떎떆媛 議고쉶븯怨 媛곸옄쓽 寃궗떎뿉꽌 엫긽쟻쑝濡 怨㏓컮濡 쟻슜븷 닔 엳뒗 쎒 湲곕컲 李멸퀬援ш컙 怨듬룞 꽕젙諛⑹븞쓣 媛쒕컻븯떎.

옱猷 諛 諛⑸쾿

1. 쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙 봽濡쒓렇옩 媛쒕컻 諛 쟻슜

李몄뿬湲곌뿉꽌 1媛 씠긽쓽 嫄닿컯씤 寃泥 寃곌낵瑜 엯젰븿쑝濡쒖뜥 李몄뿬븳 紐⑤뱺 湲곌쑝濡쒕꽣 뼸뼱吏 늻쟻맂 寃곌낵媛 諛섏쁺맂 李멸퀬援ш컙 꽕젙 寃곌낵媛 떎떆媛꾩쑝濡 議고쉶맆 닔 엳뒗 쎒 봽濡쒓렇옩쓣 媛쒕컻븯떎. 쎒쓣 넻빐 옄쑀濡寃 李몄뿬븯怨 理쒖냼 븳 紐낆쓽 嫄닿컯씤 寃泥 寃곌낵留뚯씠씪룄 쉷뱷븳떎硫 삤뵂맂 쎒쓣 넻빐 寃곌낵瑜 엯젰븯怨 룞씪븳 빆紐⑹뿉 빐 떎瑜 湲곌뿉꽌 엯젰맂 늻쟻 寃곌낵 넻빀맂 뜲씠꽣踰좎씠뒪瑜 諛뷀깢쑝濡 떎떆媛 깉濡쒖씠 꽕젙맂 李멸퀬援ш컙쓣 議고쉶빐 蹂 닔 엳뒗 李멸퀬援ш컙 怨듬룞꽕젙룄援щ 媛쒕컻븯떎.

寃궗떎 媛 꽕듃썙궧쓣 湲곕컲쑝濡 븳 李멸퀬援ш컙 怨듬룞꽕젙슜 쎒 슦遺꾪닾 꽌踰(14.04 LTS; Canonical Ltd., London, UK; http://www.ubuntu.com/) 솚寃쎌뿉꽌 nginx 1.4 (http://nginx.org)瑜 쎒 꽌踰 냼봽듃썾뼱濡 궗슜븯怨 Web Server Gateway Interface (WSGI) 꽌踰 냼봽듃썾뼱뒗 uWSGI ver. 2.0 (http://projects.unbit.it/uwsgi/)쓣 씠슜븯뿬 슫쁺븯떎. 쎒 꽌鍮꾩뒪뒗 python ver. 3.4 (http://www.python.org) 봽濡쒓렇옒諛 뼵뼱瑜 씠슜븯뿬 媛쒕컻븯떎[6,7]. 媛쒕컻뿉 씠슜븳 쎒 봽젅엫썙겕뒗 Django ver. 1.8 (Django Software Foundation; http://www.djangoproject.com/)씠硫, 李멸퀬援ш컙 꽕젙 諛 李⑦듃 옉꽦쓣 쐞븳 넻怨꾩쿂由ы봽濡쒓렇옩 numpy ver. 1.9 (http://www.numpy.org/) 紐⑤뱢怨 pandas ver. 0.16 (http://pandas.pydata.org/) 紐⑤뱢쓣 씠슜븯뿬 媛쒕컻븯떎. 궗슜옄 씤꽣럹씠뒪(user interface) 遺遺꾩 jQuery Mobile ver. 1.4 (The jQuery Foundation; http://jquerymobile.com/)쓣 湲곕컲쑝濡 媛쒕컻븯怨, 엳뒪넗洹몃옩 李⑦듃뒗 flot ver. 0.8 (http://www.flotcharts.org/) 씪씠釉뚮윭由щ 씠슜븯떎. 쎒 二쇱냼뒗 http://www.referencerange.org씠떎.

2. 봽濡쒓렇옩쓣 솢슜븳 뜲씠꽣 엯젰 諛 李멸퀬援ш컙 옄룞 꽕젙

븳援嫄닿컯愿由ы삊쉶濡쒕꽣 씡紐낇솕맂 嫄닿컯씤쓽 怨쇨굅 寃泥 寃궗寃곌낵 뜲씠꽣瑜 젣怨듬컺븘 봽濡쒓렇옩뿉 엯젰븯떎. 쎒 湲곕컲 봽濡쒓렇옩뿉 늻쟻맂 엯젰젙蹂대 諛뷀깢쑝濡 李멸퀬援ш컙 꽕젙뿉 븘슂븳 룊洹, 몴以렪李, 以묒븰媛, 理쒖냼媛, 理쒕媛믨낵 띁꽱씪쓣 룷븿븯뿬 濡쒓렇移섑솚 媛, 솢怨〓룄 寃利, 젙洹쒖꽦 寃利앷낵 늻쟻遺꾪룷 벑 넻怨꾨텇꽍씠 젣怨듬릺룄濡 븯떎[8,9]. 遺꾩꽍옄猷뚯뿉뒗 엯젰湲곌紐낃낵 洹밸떒쟻씤 痢≪젙媛(Tukey 踰뺤튃)씠 옄룞 젣嫄곕맂 痢≪젙媛믪쓣 룷븿븯뿬 寃궗빆紐, 빆紐⑸퀎 湲곌린 諛 떆빟젙蹂닿 룷븿릺룄濡 븯떎. 寃궗빆紐⑸퀎濡 嫄닿컯씤쓽 꽦蹂, 굹씠 寃궗寃곌낵媛 룷븿릺룄濡 븯떎.

寃곌낵

1. 쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙 봽濡쒓렇옩 媛쒕컻

援궡 뼱뒓 寃궗떎씠굹 떎떆媛 쎒쓣 넻빐 젒냽 諛 엯젰 媛뒫븯硫 寃궗蹂꾨줈 媛 寃궗떎뿉꽌 궗슜븯뒗 옣鍮꾩 떆빟뿉 븳 젙蹂 諛 李멸퀬 寃泥댁뿉 븳 꽦, 뿰졊 諛 痢≪젙媛 젙蹂대 媛쒖닔뿉 긽愿뾾씠 엯젰븯硫(Fig. 1), 빐떦 寃궗蹂 湲곗〈 엯젰맂 뵾뼱洹몃9쓽 늻쟻맂 뜲씠꽣媛 떎떆媛 뾽뜲씠듃릺뼱 넻怨 泥섎━맂 썑 꽕젙맂 李멸퀬援ш컙씠 議곌굔蹂꾨줈 떎떆媛 議고쉶맆 닔 엳룄濡 븯떎. 李멸퀬援ш컙 怨듬룞꽕젙쓣 쐞빐 媛쒕컻맂 쎒 빋쓽 엯젰젙蹂 솕硫 諛 떎떆媛 李멸퀬援ш컙 꽕젙솕硫댁 Fig. 2 媛숇떎.

Figure 1.

Data input page of the web-based collaboratively setting reference interval program.


Figure 2.

Statistics page for the collaborative reference interval setting of glucose test by age group, gender and institution.


2. 봽濡쒓렇옩쓣 솢슜븳 뜲씠꽣 엯젰 諛 李멸퀬援ш컙 꽕젙

쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙 봽濡쒓렇옩쓣 솢슜븯뿬 븳援嫄닿컯愿由ы삊쉶濡쒕꽣 뼸뼱吏 2016뀈怨 2017뀈 엫긽솕븰遺꾩빞 寃곌낵瑜 諛뷀깢쑝濡 媛앷쟻씠怨 넻怨꾩쟻 遺꾩꽍洹쇨굅瑜 媛뽰텣 李멸퀬援ш컙쓣 꽕젙븯떎. 湲곗큹넻怨 쇅뿉룄 寃곌낵쓽 젙洹쒕텇룷 뿬遺瑜 돺寃 뙆븙븯뿬 빐떦릺뒗 李멸퀬援ш컙쓣 諛붾줈 솗씤븷 닔 엳룄濡 븯怨 긽븳移섏 븯븳移섏뿉 90% 떊猶곌뎄媛꾩쓣 遺뿬븯떎. 쟾泥 닔媛 120紐 씠긽 뿬遺뿉 뵲씪 쟻슜릺뼱빞 븷 李멸퀬援ш컙 꽕젙諛⑸쾿씠 떖씪吏룄濡 븯怨 洹몄뿉 뵲瑜 李멸퀬援ш컙씠 젣떆맆 닔 엳룄濡 븯떎. 삉븳 뿰졊(10꽭 떒쐞) 꽦蹂 李멸퀬援ш컙씠 룆由쎌쟻쑝濡 꽕젙릺룄濡 븯떎.

遺꾩꽍옄猷뚯뿉뒗 엯젰湲곌紐낃낵 洹밸떒쟻씤 痢≪젙媛(Tukey 踰뺤튃)씠 옄룞 젣嫄곕맂 痢≪젙媛믪쓣 룷븿븯뿬 寃궗빆紐, 빆紐⑸퀎 湲곌린 諛 떆빟젙蹂닿 룷븿릺룄濡 븯떎. 寃궗빆紐⑸퀎濡 嫄닿컯씤쓽 꽦蹂, 굹씠 寃궗寃곌낵媛 룷븿릺룄濡 븯떎. 媛 빆紐⑹뿉 븳 넻怨꾨텇꽍 寃곌낵솕硫댁뿉뒗 湲곕낯쟻쑝濡 李몄뿬湲곌 닔, Tukey踰뺤뿉 洹쇨굅븳 븘썐씪씠뼱媛 젣嫄곕맂 珥 寃泥 닔 옄룞 젣嫄곕맂 븘썐씪씠뼱 닔媛 몴떆릺룄濡 븯떎.

寃궗諛⑸쾿蹂 넻怨꾨텇꽍 寃곌낵뿉꽌뒗 寃궗옣鍮꾨퀎, 寃궗떆빟蹂 遺꾩꽍긽 寃泥 닔媛 몴떆릺룄濡 븯떎. 뵾뼱洹몃9蹂 젙蹂댁뿉뒗 뿰졊蹂, 꽦蹂, 湲곌蹂 寃곌낵媛 몴떆릺룄濡 븯뒗뜲, 蹂 뿰援ъ뿉꽌뒗 뿰졊쓽 援ш컙쓣 10꽭 떒쐞濡 굹늻뼱 10꽭 誘몃쭔遺꽣 90꽭 씠긽源뚯 10媛쒖쓽 뿰졊 援ш컙뿉 븳 넻怨꾧껐怨쇨 젣떆릺룄濡 븯떎. 꽦蹂 넻怨꾨텇꽍 寃곌낵룄 궓꽦怨 뿬꽦 媛곴컖뿉 빐 넻怨꾧 씠猷⑥뼱吏룄濡 븯떎.

쟾泥 긽옄 媛 洹몃9蹂 긽옄뿉 븳 李멸퀬援ш컙 꽕젙 넻怨꾧껐怨쇰뒗 湲곕낯쟻쑝濡 媛 긽옄 닔, 룊洹좉컪, 以묒븰媛, 몴以렪李, 理쒖냼媛, 理쒕媛, 5띁꽱씪 媛믨낵 95띁꽱씪 媛믪쓣 蹂 닔 엳룄濡 븯怨, 젙洹쒕텇룷 뿬遺瑜 蹂닿린 쐞빐 긽옄 닔媛 1,000紐 誘몃쭔씠硫 Shapiro-Wilk 寃利앹쓣, 1,000紐 씠긽씠硫 Kolmogrov-Smirnov 寃利앹씠 떆뻾릺뼱 P-value뿉 뵲씪 젙洹 뿬遺瑜 뙋젙븯怨 젙洹쒕텇룷瑜 蹂댁씠吏 븡쓣 寃쎌슦 鍮꾨え닔쟻 넻怨꾧껐怨쇰 뵲瑜대룄濡 뻽떎. 긽옄뱾쓽 寃궗寃곌낵 遺꾪룷瑜 븳 늿뿉 蹂 닔 엳룄濡 엳뒪넗洹몃옩怨 늻쟻엳뒪넗洹몃옩 洹몃옒봽瑜 젣怨듯븯怨 꽦蹂, 뿰졊蹂 洹몃9 媛 寃곌낵媛믪쓽 쑀쓽븳 李⑥씠媛 엳뒗吏 蹂닿린 쐞빐 젙洹쒕텇룷 鍮꾩젙洹쒕텇룷 뿬遺뿉 뵲씪 넻怨꾧린踰뺤쓣 쟻슜븯뿬 솗씤븷 닔 엳룄濡 븯떎.

쟻슜 李멸퀬援ш컙 긽옄 닔뿉 뵲씪 떖씪吏硫 120紐 誘몃쭔씪 寃쎌슦 Robust 諛⑸쾿쓣 쟻슜븯뿬 李멸퀬援ш컙씠 꽕젙릺룄濡 븯怨 120紐 씠긽씪 寃쎌슦 젙洹쒕텇룷 뿬遺뿉 뵲씪 紐⑥닔쟻 諛⑸쾿, 鍮꾨え닔쟻 諛⑸쾿, 濡쒓렇移섑솚 諛⑸쾿 벑뿉 쓽븳 李멸퀬援ш컙씠 젣떆릺룄濡 븯떎. 젣怨듬릺뒗 李멸퀬援ш컙쓽 븯븳移섏 긽븳移 쇅뿉룄 빐떦 媛믪뿉꽌 蹂댁씪 닔 엳뒗 90% 떊猶곌뎄媛 媛믨퉴吏 젣怨듯븯뿬꽌 븯븳移섏 긽븳移섏쓽 떊猶곕룄源뚯 솗씤 媛뒫븯룄濡 븯떎.

怨좎같

蹂 뿰援ъ뿉꽌뒗 李멸퀬援ш컙 꽕젙뿉 엳뼱꽌 媛옣 겙 嫄몃┝룎씠씪 븷 닔 엳뒗 異⑸텇븳 닔쓽 嫄닿컯씤 뜲씠꽣 솗蹂 臾몄젣 李멸퀬援ш컙 꽕젙뿉 븘슂븳 넻怨꾨텇꽍쓽 쟻슜뿉 븳 臾몄젣瑜 洹쇰낯쟻쑝濡 빐寃고븷 닔 엳뒗 쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙 봽濡쒓렇옩쓣 媛쒕컻븯怨 寃궗떎씠 씠瑜 솢슜븯뿬 슜씠븯寃 李멸퀬援ш컙쓣 꽕젙븷 닔 엳룄濡 븯떎.

援궡 吏꾨떒쓽븰寃궗떎 遺遺꾩 二쇰줈 李멸퀬援ш컙 꽕젙쓣 쐞븳 寃泥 솗蹂댁쓽 뼱젮怨 李멸퀬援ш컙 꽕젙쓣 쐞븳 씤젰怨 寃궗옄썝 議곕떖쓽 뼱젮쑝濡 씤빐 寃궗떎씠 룆由쎌쟻쑝濡 李멸퀬援ш컙쓣 꽕젙븯뒗 뜲 엳뼱꽌 겙 뼱젮씠 엳怨 遺遺꾩쓽 寃궗떎씠 李멸퀬援ш컙 寃利앹쑝濡 李멸퀬援ш컙 꽕젙쓣 떊븯怨 엳떎. 寃궗떎뿉꽌 寃利앺븯뒗 李멸퀬援ш컙쓽 遺遺꾩 젣議곗궗뿉꽌 젣떆븯뒗 李멸퀬援ш컙씪 肉먮쭔 븘땲씪 젣떆맂 李멸퀬援ш컙씠 鍮꾩젙긽쟻쑝濡 꼻嫄곕굹 醫곸 寃쎌슦媛 留롮쑝굹 씠瑜 李멸퀬援ш컙 寃利앸갑踰뺣쭔쑝濡 젙솗엳 寃利앺븯湲곌 뼱젮썙 異⑸텇븳 寃利 뾾씠 洹몃濡 룄엯븯뿬 궗슜븯뒗 寃쎌슦媛 遺遺꾩씠떎.

蹂 쎒 湲곕컲 봽濡쒓렇옩쓣 넻빐 쟾援쓽 뼱뒓 寃궗떎뿉꽌굹 옄쑀濡寃 李몄뿬븯뿬 떎떆媛꾩쑝濡 李멸퀬援ш컙 怨듬룞꽕젙怨 寃곌낵뙋젙뿉 쟻슜븷 닔 嫄닿컯씤 寃泥 寃곌낵瑜 엯젰븯硫 떎瑜 寃궗떎뿉꽌 엯젰맂 늻쟻 寃곌낵 넻빀맂 뜲씠꽣踰좎씠뒪瑜 諛뷀깢쑝濡 깉濡쒖씠 꽕젙맂 李멸퀬援ш컙씠 떎떆媛 옄룞쑝濡 議고쉶릺怨, 씠뒗 寃吏 寃곌낵 뙋젙湲곗씤 李멸퀬援ш컙쑝濡 怨㏓컮濡 쟻슜맆 닔 엳쓣 肉먮쭔 븘땲씪 李멸퀬援ш컙 怨듬룞꽕젙쓽 洹쇨굅옄猷뚮줈룄 솢슜씠 媛뒫븯떎. 利 룞씪븳 옣鍮꾩 떆빟쓣 궗슜븯뒗 寃궗떎뱾濡쒕꽣 엯젰맂 寃곌낵 젙蹂닿 蹂 쎒 湲곕컲 봽濡쒓렇옩뿉 옣맖怨 룞떆뿉 봽濡쒓렇옩 옄泥댁쓽 넻怨꾨텇꽍 봽濡쒖꽭뒪뿉 쓽빐 젙젣맂 李멸퀬援ш컙 寃곌낵媛 떎떆媛 젣怨듬릺硫, 꽕젙맂 李멸퀬援ш컙 寃곌낵瑜 李몄뿬湲곌씠 떎떆媛꾩쑝濡 議고쉶븯怨 媛 寃궗떎뿉꽌 寃곌낵 뙋젙쓣 쐞븳 李멸퀬援ш컙쑝濡 怨㏓컮濡 쟻슜븷 닔 엳뒗 쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙룄援щ 留덈젴븳 寃껋뿉 쓽誘멸 엳떎.

쎒 湲곕컲 李멸퀬援ш컙 怨듬룞꽕젙 봽濡쒓렇옩쓣 넻빐 吏뿭蹂, 꽦蹂, 뿰졊蹂, 寃궗諛⑸쾿蹂, 痢≪젙湲곌린蹂 諛 떆빟蹂 李멸퀬援ш컙 꽕젙뿉 愿븳 寃곌낵 넻怨 諛 뜲씠꽣踰좎씠뒪瑜 援ъ텞븿쑝濡쒖뜥 뼢썑 븳援씤쓽 嫄닿컯젙蹂대 뙆븙븯뒗 湲곗큹젙蹂대줈 쑀슜븯寃 솢슜맆 닔 엳쓣 寃껋쑝濡 깮媛곷릺뿀떎.

蹂 쎒 봽濡쒓렇옩쓣 湲곕컲쑝濡 援궡 뿬윭 湲곌쑝濡쒕꽣 뼸뼱吏 웾쓽 嫄닿컯씤 寃泥 寃궗瑜 넻빐 떎떆媛 젙솗븳 李멸퀬援ш컙쓣 꽕젙븯怨 議고쉶븯뒗 寃껋씠 媛뒫빐議뚭퀬 뼢썑 李몄뿬湲곌쓽 濡쒓렇씤 젙蹂 벑濡앹쓣 넻빐 李몄뿬湲곌쓽 엯젰 젙蹂대 솗씤븯怨 愿由ш 媛뒫븯룄濡 蹂댁셿븷 삁젙씠떎.

蹂 뿰援ъ뿉꽌뒗 湲곗〈 李멸퀬援ш컙 꽕젙 諛 寃利앸쾿쓽 븳怨꾨 洹밸났븯湲 쐞빐 援궡 紐⑤뱺 寃궗떎씠 돺寃 李몄뿬븯怨 怨듬룞쑝濡 꽕젙맂 李멸퀬援ш컙쓣 議고쉶븯怨 쟻슜븷 닔 엳뒗 李멸퀬援ш컙 怨듬룞꽕젙쓣 쐞븳 쎒 湲곕컲 봽濡쒓렇옩쓣 媛쒕컻븯怨 援궡 寃궗떎뱾씠 젙솗븯怨 넻怨꾩쟻 洹쇨굅瑜 媛뽰텣 李멸퀬援ш컙쓣 돺怨 렪븯寃 궗슜븷 닔 엳룄濡 븯떎.

媛먯궗쓽 湲

蹂 뿰援щ뒗 2015뀈 븳엫긽寃궗젙룄愿由ы삊쉶 븰닠뿰援щ퉬 吏썝怨 븳援嫄닿컯愿由ы삊쉶 븰닠뿰援ш낵젣(2017-04) 吏썝쑝濡 씠猷⑥뼱議뚮떎

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