Bias estimate outcome of Hb parameters compared with srHb. Initial Hb showed unacceptable bias with srHb at all MDs. Cellular Hb showed no significant bias with srHb at three MDs and acceptable bias at one MD. (A) Initial Hb with srHb. (B) Cellular Hb with srHb before outlier elimination. (C) Cellular Hb with srHb after outlier elimination. Abbreviations: MD, medical decision level; CI, confidence interval; Hb, hemoglobin; srHb, saline replaced hemoglobin.