Bias estimate outcome of Hb parameters compared with the value of 1/3Hct. SrHb showed no significant bias with 1/3Hct at two MDs and acceptable bias at two MDs. Cellular Hb showed acceptable bias with 1/3Hct at all MDs. (A) Initial Hb with 1/3Hct. (B) SrHb with 1/3Hct. (C) Cellular Hb with 1/3Hct. Abbreviations: MD, medical decision level; CI, confidence interval; Hb, hemoglobin; 1/3Hct, one-third of the hematocrit; srHb, saline replaced hemoglobin.