Laboratory Medicine and Quality Assurance

Table. 1.

Clinical and laboratory characteristics in patients with cardiac troponin I and/or B-type natriuretic peptide elevation

VariablePatients with double elevations (N=135)Patients with only cTnI elevation (N=118)Patients with only BNP elevation (N=343)

cTnI (+)/BNP (+)*cTnI (+)/BNP (-)*P-valuecTnI (-)/BNP (+)*P-value
Age (yr)74.2±11.261.9±16.8<0.00172.4±13.10.145
Length of ED stay (min)228 (151–345)200 (103-326)0.112263 (185–345)0.026
Admission rate after ED visit (%)78.5 (106/135)62.7 (74/118)0.00667.3 (231/343)0.016
Length of hospital stay after admission (day)11 (5–19)6 (3–13)0.00110 (5–20)0.761
Readmission rate within 3 months of discharge (%)17.9 (19/106)10.8 (8/74)0.18816.5 (38/231)0.737
Mortality rate within 1 year (%)17.0 (19/112)17.9 (14/78)0.86012.7 (31/245)0.276
cTnI (ng/mL, half-life about 2 hr)0.07 (0.04–0.18)0.05 (0.03–0.19)0.4290.01 (0.01–0.01)-
BNP (pg/mL, half-life 20 min)430 (228–727)23 (9–46)-194 (140–322)<0.001

Values are presented as mean±SD, median (interquartile range), or percentage (number of patients/total patients included in the analysis).

Abbreviations: cTnI, cardiac troponin I; BNP, B-type natriuretic peptide; ED, emergency department.

The 99th percentile of cardiac troponin I is 0.02 ng/mL. Thus, values ≥0.03 ng/mL were considered positive. The cutoff for BNP is 100 pg/mL.

P-values were calculated in comparison with the patients with both cardiac marker elevations.

Mortality rate was calculated after excluding the patients with follow-up loss.

J Lab Med Qual Assur 2017;39:83~89
© Lab Med Qual Assur