Range of hemolysis score calculation for identifying mechanical hemolysis
| Score | MCHC (g/dL) | MPV (fL) | RBC ghost (106cells/µL) | mHb-cHb (g/dL) | MCHC-CHCM (g/dL) |
|---|---|---|---|---|---|
| 0 | <34 | <7.3 | <0.02 | <0.13 | <0.26 |
| 1 | 34≤ <36.3 | 7.3≤ <7.8 | 0.02≤ <0.03 | 0.13≤ <0.39 | 0.26≤ <0.96 |
| 2 | 36.3≤ <38.5 | 7.8≤ <8.5 | 0.03≤ <0.04 | 0.38≤ <1.31 | 0.96≤ <3.35 |
| 3 | ≥38.5 | ≥8.5 | ≥0.04 | ≥1.31 | ≥3.35 |
Abbreviations: MCHC, mean corpuscular hemoglobin concentration; MPV, mean platelet volume; RBC, red blood cell; mHb, measured hemoglobin; cHb, calculated hemoglobin; CHCM, corpuscular hemoglobin concentration mean.
Example of hemolysis score calculation: If MCHC 35 g/dL, MPV 7.9 fL, RBC ghost 0.03×106 cells/μL, mHb-cHb 0.5 g/dL, and MCHC-CHCM 1 g/dL, new algorithm is MPV(2)+RBC ghost(2)+mHb-cHb(2)+MCHC-CHCM(2)=8 and old algorithm is MCHC(1)+RBC ghost(2)+mHb-cHb(2)+MCHC-CHCM(2)=7.