Laboratory Medicine and Quality Assurance

Table. 3.

Trend of methods used in syphilis serology proficiency testing in 2018–2019

Serologic tests for syphilis Methods 2018 2019


1st trial 2nd trial 1st trial 2nd trial
Nontreponemal VDRL 54 (9.4) 54 (9.4) 53 (9.0) 54 (9.2)
RPR card 299 (51.9) 298 (51.8) 301 (51.3) 300 (51.0)
RPR TIA 206 (35.8) 206 (35.8) 218 (37.1) 222 (37.8)
RPR unknown 17 (3.0) 17 (3.0) 15 (2.6) 12 (2.0)
Total 576 (100.0) 575 (100.0) 587 (100.0) 588 (100.0)
Treponemal FTA-ABS 12 (4.3) 12 (4.3) 12 (4.3) 12 (4.3)
TPPA 103 (37.2) 96 (34.7) 92 (33.0) 86 (30.7)
TPLA* 43 (15.5) 42 (15.2) 44 (15.8) 45 (16.1)
CLIA 42 (15.2) 48 (17.3) 48 (17.2) 46 (16.4)
ICA 72 (26.0) 73 (26.4) 76 (27.2) 85 (30.4)
Unknown 5 (1.8) 6 (2.2) 7 (2.5) 6 (2.1)
Total 277 (100.0) 277 (100.0) 279 (100.0) 280 (100.0)

Values are presented as numbers (%).

Abbreviations: VDRL, Venereal Disease Research Laboratory; RPR, rapid plasma reagin; TIA, turbidimetric immunoassay; FTA-ABS, fluorescent treponemal antibody absorption; TPPA, Treponema pallidum particle agglutination; TPLA, Treponema pallidum latex agglutination; CLIA, chemiluminescence immunoassay; ICA, immunochromatographic assay.

*TPLA is one of the automated treponemal tests based on TIA.

Lab Med Qual Assur 2021;43:56~64 https://doi.org/10.15263/jlmqa.2021.43.2.56
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