Laboratory Medicine and Quality Assurance

Table. 1.

Tests used for checking homogeneity, stability, and adequacy of control specimens for syphilis serology proficiency

Serologic tests for syphilis Methods Instruments Reagents
Nontreponemal RPR TIA Cobas 8000 Mediace RPR
RPR card Manual Asan RPR Card Test
BD Macro-Vue RPR Card Test
ASI RPR Card Test for Syphilis
Treponemal TPPA Manual SERODIA-TPPA
TPLA* Cobas 8000 Mediace TPLA
ICA Manual SD Syphilis Fast 3.0
FTA-ABS Manual ZEUS Scientific

The instrument used was from the following company: Cobas 8000 (Roche Diagnostic, Basel, Switzerland).

Abbreviations: RPR, rapid plasma reagin; TIA, turbidimetric immunoassay; TPPA, Treponema pallidum particle agglutination; TPLA, Treponema pallidum latex agglutination; ICA, immunochromatographic assay; FTA-ABS, fluorescent treponemal antibody absorption.

*TPLA is one of the automated treponemal tests based on TIA.

Lab Med Qual Assur 2021;43:56~64
© Lab Med Qual Assur