Table. 2.

Acceptance rates for the variants of the intended response

Specimen Gene Variant of intended response Acceptance rate* (%)

Transcript Nucleotide change Protein change
GNS-18-01 CEBPA NM_004364.4 c.430dupG p.Glu144GlyfsTer26 9/10 (90.0)
IDH1 NM_005896.2 c.394C>G p.Arg132Gly 12/12 (100.0)
NPM1 NM_002520.6 c.860_863dupTCTG p.Trp288CysfsTer12 11/12 (91.7)
GNS-18-02 CEBPA NM_004364.4 c.282_312del p.Val95ThrfsTer55 9/11 (81.8)
IKZF1 NM_006060.5 c.14_17dupAGGG p.Gln7GlyfsTer21 9/10 (90.0)
GNS-18-03 KIT NM_000222.2 c.2447A>T p.Asp816Val 9/9 (100.0)
GNS-18-04 DNMT3A NM_022552.4 c.2645G>A p.Arg882His 12/12 (100.0)
FLT3 NM_004119.2 c.1784_1804dup p.Arg595_Leu601dup 11/11 (100.0)
NPM1 NM_002520.6 c.860_863dup p.Trp288CysfsTer12 12/12 (100.0)
GNS-19-01 CALR NM_004343.3 c.1154_1155insTTGTC p.Lys385AsnfsTer47 12/12 (100.0)
GNS-19-02 NPM1 NM_002520.6 c.863_864insCATG p.Trp288Cysfs*12 12/14 (85.7)
NRAS NM_002524.4 c.182A>G p.Gln61Arg 15/15 (100.0)
GNS-19-03 JAK2 NM_004972.3 c.1849G>T p.Val617Phe 13/13 (100.0)
GNS-19-04 TP53 NM_000546.5 c.833C>T p.Pro278Leu 18/18 (100.0)
GNS-20-01 CEBPA NM_004364.4 c.324C>A p.Tyr108Ter 14/14 (100.0)
TET2 NM_001127208.2 c.4393C>T p.Arg1465Ter 15/15 (100.0)
GNS-20-02 IDH2 NM_002168.2 c.419G>A p.Arg140Gln 21/21 (100.0)
NRAS NM_002524.4 c.37G>C p.Gly13Arg 20/20 (100.0)
GNS-20-03 TP53 NM_000546.5 c.818G>A p.Arg273His 17/17 (100.0)
GNS-20-04 IDH2 NM_002168.2 c.419G>A p.Arg140Gln 19/21 (90.5)
NPM1 NM_002520.6 c.860_863dup p.Trp288CysfsTer12 20/21 (95.2)

Values are presented as number (%), unless otherwise stated.

*The acceptance rate is calculated as the number of participants achieving an acceptable result per the total participants.

Lab Med Qual Assur 2021;43:65~71 https://doi.org/10.15263/jlmqa.2021.43.2.65
© Lab Med Qual Assur