Table. 3.

Non-evaluable variants

Variable Category No.
No. of specimen with non-evaluable variant 9/12
Total no. of non-evaluable variants 17
Characteristics of non-evaluable variants
Data type Electronic data 9
DNA 8
Variant type Single nucleotide variant 9
Insertion/deletion variant 8
Gene ASXL1 3
RUNX1 3
TET2 3
CEBPA 2
BCR 1
CSF3R 1
DNMT3A 1
KMT2A 1
MYD88 1
Cause of non-evaluation* Concordance rate <80% 17
Conflict on the variant classification 5
Confirmed as false negative 3
Low VAF close to the detection limit 1
Technical issue of NGS 1

Abbreviations: VAF, variant allele frequency; NGS, next-generation sequencing.

*Duplicate counts were made for the causes of non-evaluable variants.

Lab Med Qual Assur 2021;43:65~71 https://doi.org/10.15263/jlmqa.2021.43.2.65
© Lab Med Qual Assur