Laboratory Medicine and Quality Assurance

Table. 1.

Critical differences based on clinician’s questionnaire (II)

Items Unit Sex No. of responses Decision level Median value* CD (%)
AFP ng/mL F 59 10 15 50.0
M 64 100 120 20.0
CA125 U/mL F 55 35 45 28.6
CA15-3 U/mL F 56 25 35 40.0
CA19-9 U/mL F 60 37 45 21.6
M 62 100 120 20.0
CEA ng/mL F 61 5 10 100.0
M 64 35 42 20.0
PSA, total μg/L M 55 4 5 25.0
M 53 10 12 20.0
Free PSA % M 46 25 30 20.0
M 43 10 12.5 25.0
T3 ng/dL F 54 80 70 12.5
F 54 200 220 10.0
F 54 230 200 13.0
M 55 50 80 60.0
T4 μg/dL F 54 3 2.5 16.7
F 54 13 15 15.4
F 54 14 12 14.3
M 55 3.5 4.6 31.4
Free T4 ng/dL F 60 0.8 0.7 12.5
F 61 4 4.5 12.5
F 60 2 1.7 15.0
M 60 0.5 0.94 88.0
Thyroglobulin ng/mL F 52 0.05 1.95 3800.0
M 50 77 90 16.9
TSH mIU/L F 60 5 7 40.0
F 61 0.5 0.27 46.0
F 58 0.1 0.27 170.0
M 58 7.5 4.35 42.0
Estradiol pg/mL F 47 60 72 20.0
F 43 5 20 300.0
F 43 450 420 6.7
F 43 3000 2000 33.3
M 42 60 60 0.0
M 41 450 350 22.2
FSH mIU/mL F 48 95 134.9 42.0
F 43 0.1 2.5 2400.0
F 41 10 16 60.0
F 43 200 150 25.0
M 41 1 1.5 50.0
M 41 35 27 22.9
M 41 95 70 26.3
LH mIU/mL F 47 55 70 27.3
F 43 0.3 5 1566.7
F 43 6 12 100.0
F 43 200 150 25.0
M 41 1 2 100.0
M 41 50 40 20.0
M 41 100 70 30.0
Testosterone ng/mL M 49 10 15 50.0
F 44 0.025 0.0775 210.0
F 42 10 6 40.0
F 42 15 10 33.3
M 43 0.9 2 122.2
M 43 10 9 10.0
Prolactin ng/mL F 50 15 20 33.3
M 51 15 20 33.3
M 50 200 100 50.0
F 41 200 150 25.0

Abbreviations: CD, critical difference; F, female; M, male; AFP, alpha-fetoprotein; CA, cancer antigen; CEA, carcinoembryonic antigen; PSA, prostate-specific antigen; T3, tri-iodothyronine; T4, thyroxine; TSH, thyroid-stimulating hormone; FSH, follicle-stimulating hormone; LH, luteinizing hormone

*The median value of the answered value in the clinician’s questionnaire. †CD=(median value–decision level)×100/decision level

Lab Med Qual Assur 2022;44:88~98 https://doi.org/10.15263/jlmqa.2022.44.2.88
© Lab Med Qual Assur