Laboratory Medicine and Quality Assurance

Table. 4.

Mean bias of participants of the accuracy-based creatinine proficiency testing program based on the eGFR

Year-round Specimen name eGFR

CKD-EPI MDRD 4 variable (IDMS-traceable)


No. of participants* Target value (mL/min/1.73 m2) Mean bias (%) No. of participants* Target value (mL/min/1.73 m2) Mean bias (%)
2020-1st CAC-20-01 88 59.9 –3.6 443 53.7 –0.7
CAC-20-02 92 29.5 3.5 427 27.7 5.3
CAC-20-03 89 10.0 3.4 429 10.5 4.5
2020-2nd CAC-20-04 92 35.2 3.7 452 31.4 4.3
CAC-20-05 98 21.4 2.6 455 20.2 3.4
CAC-20-06 90 13.5 2.9 454 13.0 3.5
2021-1st CAC-21-01 96 91.9 –4.7 457 78.5 –3.2
CAC-21-02 97 64.1 –0.3 441 57.5 1.5
CAC-21-03 93 31.6 –0.6 453 29.2 1.2
2021-2nd CAC-21-04 114 89.7 –3.9 433 85.8 –3.1
CAC-21-05 117 68.7 –1.9 414 62.9 0.2
CAC-21-06 114 32.7 –1.2 427 30.7 0.4

Abbreviations: eGFR, estimated glomerular filtration rate; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; IDMS, isotope-dilution mass spectrometry; IQR, interquartile range; Q1, 25th percentile; Q3, 75th percentile.

*Number of participants without outlier; The outliers were defined as less than Q1–1.5×IQR or greater than Q3+1.5×IQR and were excluded from analysis.

Lab Med Qual Assur 2022;44:136~142 https://doi.org/10.15263/jlmqa.2022.44.3.136
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