Proficiency testing results for organic acid analysis (unit, mmol/mol creatinine)
| Year | Trial | Specimen no. | Intended response | Reported response | No. | Reported components | No. | Median | Minimum | Maximum |
|---|---|---|---|---|---|---|---|---|---|---|
| 2020 | 1st | CMO-20-01 | Tyrosinemia type I | Tyrosinemia type I | 4 | 4-Hydroxyphenylacetic | 4 | 388.8 | 298.3 | 487.9 |
| 4-Hydroxyphenyllactic | 3 | 708.6 | 307.1 | 985.4 | ||||||
| 4-Hydroxyphenylpyruvic | 4 | 678.9 | 352.5 | 834.2 | ||||||
| 4-OH phenyllactic acid | 1 | 561.3 | ||||||||
| Lactic | 1 | 119.5 | ||||||||
| Succinylacetone | 4 | 813.2 | 585.1 | 55,604.9 | ||||||
| CMO-20-02 | Ketosis | Ketosis | 4 | 3-Hydroxybutyric | 4 | 231 | 63.9 | 831 | ||
| Acetoacetic | 3 | 696.7 | 115 | 1,763.5 | ||||||
| Lactic | 1 | 157 | ||||||||
| CMO-20-03 | No abnormality | No abnormality | 3 | |||||||
| Others | 1 | Lactic | 1 | 171.8 | ||||||
| 2nd | CMO-20-04 | Short chain acyl CoA dehydrogenase deficiency | Short chain acyl CoA dehydrogenase deficiency | 3 | 3-Hydroxybutyric | 4 | 175 | 106.1 | 230 | |
| Ethylmalonic encephalopathy | 1 | Methylsuccinic | 3 | 56.6 | 33.6 | 69.6 | ||||
| CMO-20-05 | Propionic acidemia | Propionic acidemia | 4 | 3-Hydroxypropionic | 4 | 725.9 | 342 | 2,459 | ||
| Ethylmalonic | 4 | 289.2 | 56.5 | 769.5 | ||||||
| Methylcitric | 4 | 150.1 | 41 | 296.3 | ||||||
| Propionylglycine | 4 | 195.6 | 99.9 | 356.2 | ||||||
| CMO-20-06 | No abnormality | No abnormality | 4 | |||||||
| 2021 | 1st | CMO-21-01 | Ornithine transcarbamylase deficiency | Ornithine transcarbamylase deficiency | 3 | Orotic | 3 | 101.5 | 86.7 | 447.3 |
| No abnormality | 1 | Uracil | 3 | 54.8 | 43.4 | 275.8 | ||||
| CMO-21-02 | No abnormality | No abnormality | 3 | |||||||
| Urea cycle disorder | 1 | Orotic | 1 | 18.3 | ||||||
| CMO-21-03 | No abnormality | No abnormality | 4 | |||||||
| 2nd | CMO-21-04 | Methylmalonic acidemia | Methylmalonic acidemia | 4 | 3-Hydroxypropionic | 4 | 259.2 | 172.5 | 406.7 | |
| Methylmalonic | 4 | 530.4 | 233.9 | 905 | ||||||
| Methylcitric | 4 | 95.1 | 7.1 | 166.3 | ||||||
| CMO-21-05 | No abnormality | No abnormality | 4 | |||||||
| CMO-21-06 | No abnormality | No abnormality | 4 |