Cut-off values used for expanded neonatal screening tests using tandem mass spectrometry in the first trial in 2020
| Variable | Unit | Mean | Median | Minimum | Maximum | No. of institutions |
|---|---|---|---|---|---|---|
| Amino acids | ||||||
| Alanine | umol/L | 728.5 | 734.9 | 440.0 | 996.0 | 14 |
| Arginine | umol/L | 57.7 | 62.6 | 31.0 | 76.2 | 14 |
| Aspartate | umol/L | 130.0 | 175.0 | 2 | ||
| Citrulline | umol/L | 45.4 | 45.9 | 28.7 | 60.0 | 14 |
| Glutamate | umol/L | 700.0 | 450.8 | 850.0 | 7 | |
| Glycine | umol/L | 964.3 | 1,013.0 | 441.2 | 1,353.5 | 14 |
| Histidine | umol/L | 212.1 | 185.6 | 89.5 | 583.3 | 10 |
| Leucine+isoleucine | umol/L | 294.7 | 303.9 | 200.0 | 349.1 | 14 |
| Methionine | umol/L | 57.4 | 58.6 | 28.0 | 86.5 | 14 |
| Ornithine | umol/L | 309.5 | 300.0 | 180.0 | 449.5 | 14 |
| Phenylalanine | umol/L | 114.9 | 109.5 | 89.6 | 139.3 | 14 |
| Proline | umol/L | 410.8 | 384.5 | 181.9 | 800.0 | 13 |
| Tyrosine | umol/L | 275.4 | 289.6 | 169.7 | 357.5 | 14 |
| Valine | umol/L | 273.8 | 280.6 | 187.6 | 368.6 | 14 |
| Methionine/phenylalanine | 1.0 | 0.6 | 1.5 | 9 | ||
| Phenylalanine/tyrosine | 2.1 | 1.67 | 8.7 | 9 | ||
| Acylcarnitines | ||||||
| C0 | umol/L | 63.256 | 60.83 | 43.24 | 90.00 | 14 |
| C2 | umol/L | 49.983 | 49.21 | 35.74 | 74.21 | 13 |
| C3 | umol/L | 5.379 | 5.35 | 3.73 | 6.90 | 14 |
| C4 | umol/L | 0.639 | 0.60 | 0.41 | 1.40 | 14 |
| C5 | umol/L | 0.659 | 0.66 | 0.27 | 1.10 | 14 |
| C6 | umol/L | 0.230 | 0.20 | 0.10 | 0.52 | 13 |
| C8 | umol/L | 0.303 | 0.29 | 0.12 | 0.52 | 14 |
| C10 | umol/L | 0.315 | 0.32 | 0.15 | 0.56 | 14 |
| C12 | umol/L | 0.383 | 0.30 | 0.16 | 0.80 | 13 |
| C14 | umol/L | 0.581 | 0.49 | 0.40 | 0.92 | 13 |
| C16 | umol/L | 5.883 | 5.74 | 4.70 | 7.50 | 14 |
| C18 | umol/L | 1.822 | 1.83 | 1.50 | 2.05 | 13 |
| C5DC | umol/L | 0.271 | 0.30 | 0.14 | 0.35 | 13 |
| C5OH | umol/L | 0.666 | 0.60 | 0.45 | 1.03 | 12 |
| C3/C2 | umol/L | 0.30 | 0.20 | 0.38 | 9 | |
| C5/C3 | umol/L | 0.92 | 0.32 | 2.26 | 8 | |
| C8/C10 | umol/L | 2.50 | 1.23 | 3.55 | 5 | |
| C5/C0 | umol/L | 0.03 | 0.01 | 0.05 | 5 | |
| C5/C2 | umol/L | 0.06 | 0.02 | 0.31 | 8 | |
| C8/C2 | umol/L | 0.03 | 0.01 | 0.09 | 8 |