Analytical instrument conditions for tandem mass spectrometry (multiple reaction monitoring condition)
| Compound | Q1 (precursor ion, m/z) | Q3 (product ion, m/z) | Dwell time (ms) | Declustering potential (V) | Entrance potential (V) | Collision energy (V) | Collision cell exit potential (V) |
|---|---|---|---|---|---|---|---|
| Levetiracetam | 171.0 | 126.0 | 80 | 46 | 10 | 21 | 10 |
| Levetiracetam-IS | 177.1 | 132.1 | 80 | 41 | 10 | 21 | 8 |
| Lamotrigine | 256.0 | 210.9 | 80 | 111 | 10 | 37 | 14 |
| Lamotrigine-IS | 262.1 | 216.8 | 80 | 45 | 9 | 39 | 7 |
Abbreviations: m/z, mass-to-charge ratio; IS, internal standard.