Laboratory Medicine and Quality Assurance

Table. 3.

Trend of methods used in the syphilis serology proficiency testing between 2020–2021

Serologic tests for syphilis Methods 2020 2021
1st trial 2nd trial 1st trial 2nd trial
Non-treponemal VDRL 57 (9.8) 58 (9.9) 55 (9.4) 59 (10.0)
RPR card 280 (47.9) 273 (46.4) 266 (45.5) 268 (45.1)
RPR TIA 236 (40.4) 245 (41.7) 255 (43.7) 257 (43.3)
RPR unknown 11 (1.9) 12 (2.0) 8 (1.4) 10 (1.7)
Total 584 (100.0) 588 (100.0) 584 (100.0) 594 (100.0)
Treponemal TPPA 79 (28.6) 86 (31.0) 80 (28.6) 52 (19.5)
ICA 87 (31.5) 67 (24.2) 57 (20.4) 69 (25.9)
CLIA 50 (18.1) 51 (18.4) 52 (18.6) 55 (20.7)
TPLA* 46 (16.7) 50 (18.1) 50 (17.9) 51 (19.2)
FTA-ABS 12 (4.3) 12 (4.3) 12 (4.3) 12 (4.5)
Unknown 2 (0.7) 11 (4.0) 29 (10.4) 27 (10.2)
Total 276 (100.0) 277 (100.0) 280 (100.0) 266 (100.0)

Values are presented as number (%).

Abbreviations: VDRL, Venereal Disease Research Laboratory test; RPR, rapid plasma reagin test; TIA, turbidoimmunoassay test; TPPA, Treponema pallidum particle agglutination test; ICA, immunochromatographic assay test; CLIA, chemiluminescence immunoassay test; TPLA, Treponema pallidum latex agglutination test; FTA-ABS, fluorescent treponemal antibody-absorption test.

*TPLA is one of the automated treponemal tests based on TIA.

Lab Med Qual Assur 2023;45:98~106 https://doi.org/10.15263/jlmqa.2023.45.3.98
© Lab Med Qual Assur