Laboratory Medicine and Quality Assurance

Table. 1.

Within-run and between-run precision analyses for normal and abnormal high-level and low-level quality control material

Variable Normal control Abnormal high-level control Abnormal low-level control Manufacturer’s limit, CV (%) State-of-the-art, CV (%)
Mean CV (%) Mean CV (%) Mean CV (%)
Within-run
WBC (×109/L) 8.7 0.97 21.1 0.91 3.2 1.21 3 2.5/1.5/2.5
Neutrophils (×109/L) 4.78 1.49 13.61 1.59 1.45 2.09 3.5 2.5
Eosinophils (×109/L) 0.63 8.36 1.12 8.4 0.14 7.64 13.5 10
Basophils (×109/L) 0.003 39.19 0.015 40.64 0.001 56.42 - 20
Lymphocytes (×109/L) 2.49 2.48 3.15 3.46 1.37 1.1 5 3.5
Monocytes (×109/L) 0.77 3.71 3.16 2.88 0.29 4.38 10 8.5
RBC (×1012/L) 3.96 1.3 5.26 0.51 1.77 0.5 1.5 1.1
Hb (g/dL) 11.7 0.29 15.4 0.35 4.7 0.37 1.5 0.9
MCV (fL) 88.03 0.21 89.05 0.19 80.99 0.17 1 0.6
RDW (%) 15.4 0.53 15.97 0.74 15.25 0.97 2.5 2.0
Platelets (×109/L) 206 1.21 402 1.88 69 2.15 3.5 3.0
MPV (fL) 9.76 0.82 10.08 0.57 9.46 0.55 2.5 2.5
MDW (units) 37.97 2.3 37.44 2.44 36.73 2.58 10 -
Between-run
WBC (×109/L) 8.8 1.3 21.3 1.05 3.3 1.28 3 2.5/1.5/2.5
Neutrophils (×109/L) 4.9 1.9 13.8 1.51 1.5 1.91 3.5 2.5
Eosinophils (×109/L) 0.52 5.22 1.15 5.28 0.14 6.55 13.5 10
Basophils (×109/L) 0.005 98.07 0.019 37.7 0.001 148.79 - 20
Lymphocytes (×109/L) 2.5 2.53 3.1 3.49 1.4 2.28 5 3.5
Monocytes (×109/L) 0.79 4.42 3.3 2.95 0.29 4.31 10 8.5
RBC (×1012/L) 3.94 0.86 5.32 1.09 1.79 1 1.5 1.1
Hb (g/dL) 11.8 0.67 15.6 0.51 4.8 0.35 1.5 1.0
MCV (fL) 88.05 0.32 89.07 0.28 81.01 0.31 1 0.8
RDW (%) 15.44 1.04 16.03 1.04 15.34 1.18 2.5 2.0
Platelets (×109/L) 208 1.91 404 1.49 70 1.87 3.5 3.0
MPV (fL) 9.79 0.56 10.07 0.59 9.47 0.66 2.5 2.5
MDW (units) 37 2.76 38.3 2.45 36.7 2.41 10 -

Abbreviations: CV, coefficient of variation; WBC, white blood cells; RBC, red blood cells; Hb, hemoglobin; MCV, mean corpuscular volume; MDW, monocyte distribution width; MPV, mean platelet volume; RDW, red cell distribution width.

Lab Med Qual Assur 2023;45:149~155 https://doi.org/10.15263/jlmqa.2023.45.4.149
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