Laboratory Medicine and Quality Assurance

Table. 7.

Distribution of clinical data and difference of RI between methods according to the change of RI before and after recalibration

Variable Central percentiles for RI Before recalibration After recalibration
RI Distribution (low, RI, high) RI Distribution (low, RI, high)
TSH (μIL/mL)
A 99.0 0.35–4.94 4, 58, 44 0.39–5.53 4, 58, 44
B 97.5 0.38–5.33 4, 54, 48 0.42–5.54 4, 54, 48
C 95.0 0.27–4.20 4, 49, 53 0.23–3.66 4, 49, 53
Difference (LL/UL)* 0.11/1.13 0.19/1.88
T3 (ng/mL)
A 95.0 0.64–1.52 4, 41, 38 0.77–1.74 4, 41, 38
B 95.0 0.87–1.78 12, 48, 23 0.90–1.81 12, 48, 23
C 95.0 0.80–2.00 5, 52, 26 0.66–1.75 5, 52, 26
Difference (LL/UL)* 0.23/0.48 0.24/0.07
FT4 (ng/dL)
A 99.0 0.70–1.48 0, 42, 37 0.75–1.63 0, 42, 37
B 95.0 0.61–1.12 1, 33, 45 0.74–1.30 1, 33, 45
C 95.0 0.93–1.70 0, 34, 45 0.75–1.41 0, 34, 45
Difference (LL/UL)* 0.32/0.58 0.01/0.33

Abbreviations: RI, reference interval; TSH, thyroid stimulating hormone; T3, triiodothyronine; FT4, free thyroxine; LL, lower limit; UL, upper limit.

*Differences between the minimum and maximum values of the LL and UL of the RI.

Lab Med Qual Assur 2024;46:214~224 https://doi.org/10.15263/jlmqa.2024.46.4.214
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