Performance Evaluation of Infusion Systems for Red Blood Cell Transfusion

Min-Sun Kim; Jin Seok Kim; Eunyoung Lim; Hongchul Park; Sang-Hyun Hwang; Heung-Bum Oh; Dae-Hyun Ko

doi:10.15263/jlmqa.2019.41.3.161

Article

View

Original Article

J Lab Med Qual Assur 2019; 41(3): 161-165

Published online September 30, 2019

https://doi.org/10.15263/jlmqa.2019.41.3.161

Performance Evaluation of Infusion Systems for Red Blood Cell Transfusion

Min-Sun Kim¹, Jin Seok Kim¹, Eunyoung Lim², Hongchul Park³, Sang-Hyun Hwang¹, Heung-Bum Oh¹, and Dae-Hyun Ko¹

¹Department of Laboratory Medicine, ²Children’s Hospital Nursing Team, and ³Biomedical Engineering, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Correspondence to:Dae-Hyun Ko
Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea
Tel: +82-2-3010-4504 Fax: +82-2-478-0884 E-mail: daehyuni1118@amc.seoul.kr

Received: March 22, 2019; Revised: August 21, 2019; Accepted: August 22, 2019

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Go to

Abstract

Background:

Transfusion in neonates and infants can be performed using an electro-mechanical infusion system that has appropriate accuracy in terms of flow rate, volume, and bolus. However, there are no infusion systems approved for transfusion in Korea. In this study, we evaluate the performance of two electromechanical infusion systems for transfusion in pediatric patients.

Methods:

We tested two systems, Baxter and Terumo, using 9 units of leukocyte-filtered red blood cells. The blood samples were delivered through the systems at constant speeds of 10, 30, and 100 mL/hr, and the accuracy in terms of the delivered volume was estimated. Before and after infusion, hemoglobin, hematocrit, plasma hemoglobin, potassium, and lactate dehydrogenase levels were measured in each sample. The percentage of hemolysis (%Hemolysis) was calculated to evaluate the safety of the infusion systems.

Results:

For Terumo, the mean error rate of the infused volume was less than 5%. We expect that Terumo can transfuse blood at a volume close to the set volume. Further, both infusion systems showed acceptable %Hemolysis levels (mean±standard deviation: Terumo, 0.14±0.04; Baxter, 0.17±0.06).