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pISSN 2950-9114 eISSN 2950-9122
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Report On Proficiency Testing

Lab Med Qual Assur 2020; 42(1): 1-9

Published online March 31, 2020


Copyright © Korean Association of External Quality Assessment Service.

Report of the Korean Association of External Quality Assessment Service on Autoimmune Testing (2018–2019)

Hee-Jung Chung1, Hee-Won Moon1, and Joowon Yi2

1Department of Laboratory Medicine, Konkuk University School of Medicine; 2Samkwang Medical Laboratories, Seoul, Korea

Correspondence to:Hee-Won Moon
Department of Laboratory Medicine, Konkuk University Medical Center, 120- 1 Neungdong-ro, Gwangjin-gu, Seoul 05030, Korea
Tel +82-2-2030-5583 Fax +82-2-2030-7498 E-mail hannasis@hanmail.net

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Under the Korean Association of External Quality Assessment Service, autoimmune proficiency testings (PT) for six test items were performed in 2018–2019 for laboratory quality improvement. We conducted two trials per year and sent three PT materials for anti-nuclear antibody (ANA) testing and two PT materials for anti-mitochondrial antibody (AMA), anti-smooth muscle antibody (SMA), anti-thyroglobulin antibody (anti-Tg), anti-thyroperoxidase antibody (anti-TPO), and anti-double stranded DNA antibody (anti-dsDNA) testing in each trial. The analysis was conducted based on the information and results of each test item entered by the laboratory. The report comprised of a common report that showed the characteristics of all the participating laboratories and a laboratory-specific report that showed the assessment data of individual laboratories. The intended response rates for ANA, AMA, SMA, and anti-dsDNA qualitative tests were over 97.5%, 88.2%, 85.0%, and 90.4%, respectively. The coefficient of variations for anti-Tg and anti-TPO was 10.4%–70.1% and 16.6%–21.0%, respectively. The number of participating laboratories in 2019 was more than that in 2018. We believe this statistical report will be useful to interpret external PT results and set up autoimmune assays at each laboratory.

Keywords: Korean Association of External Quality Assessment Service, Laboratory proficiency testing, Quality improvement, Immunology, Autoimmune diseases, Autoimmune antibodies

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