Lab Med Qual Assur 2022; 44(1): 29-35
Published online March 31, 2022
Copyright © Korean Association of External Quality Assessment Service.
A-Jin Lee1 , Seong Gyu Kim2 , and Chang-Ho Jeon1
1Department of Laboratory Medicine and 2Division of Nephrology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea
Correspondence to:Chang-Ho Jeon
Department of Laboratory Medicine, Daegu Catholic University School of Medicine, 33 Duryugongwon-ro 17-gil, Nam-gu, Daegu 42472, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: In this study, after reporting the urine sediment, the clinical utility of the results was analyzed to broaden the clinical usefulness of urine sediment.
Methods: This study included 114 patients with renal impairment who tested positive for pathological urine sediment at the Catholic Medical Center in Daegu from January 2020 to November 2020. Urine test strips and urine sediment tests were performed, and the estimated glomerular filtration rate (eGFR), blood urea nitrogen, and creatinine were measured. The patient’s clinical diagnosis was confirmed by examining medical records, and the clinical usefulness of the pathological urine sediment was analyzed.
Results: Albumin, red blood cells (RBCs), RBC cast, and broad cast showed a positive rate of 92% or more on urinalysis. In patients with a normal eGFR, albumin, RBC cast, RBC, and broad cast showed a positive rate of 8.8% or more. Broad cast, albumin, RBC cast, and ketone levels were significantly correlated with eGFR. A total of 72.6% of broad casts were found in patients with acute renal disease. The eGFR decreased in 27.8% of the 18 patients with acute kidney injury, and abnormal findings in these patients’ the urine stick and sediment preceded the eGFR results.
Conclusions: The microscopic urine sediment test showed better results than the urine stick test for detecting leukocytes, and 9.6% of patients with normal eGFR were found to be positive. Because urine sediment tests can detect various pathological sediments, it is necessary to activate the urine sediment test.
Keywords: Urine, Sediment, Urinalysis, Microscopy
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