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pISSN 2950-9114 eISSN 2950-9122
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Original Article

Lab Med Qual Assur 2022; 44(2): 99-104

Published online June 30, 2022

https://doi.org/10.15263/jlmqa.2022.44.2.99

Copyright © Korean Association of External Quality Assessment Service.

A Pilot Project for the Expansion of the External Quality Assessment Program in Transfusion Medicine: Anti-D Titer Test

Yousun Chung1 , Jin Seok Kim2 , Hee-Jeong Youk2 , Sang-Hyun Hwang2 , Heung-Bum Oh2 , Hyungsuk Kim3 , and Dae-Hyun Ko2

1Department of Laboratory Medicine, Kangdong Sacred Heart Hospital; 2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine; 3Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea

Correspondence to:Dae-Hyun Ko
Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea
Tel +82-2-3010-4504
E-mail daehyuni1118@amc.seoul.kr

Hyungsuk Kim
Department of Laboratory Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea
Tel +82-2-2072-3500
E-mail hyungsuk_kim@snuh.org

Received: November 22, 2021; Revised: December 22, 2021; Accepted: December 22, 2021

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: Many test items in transfusion medicine that are still not included in the Korean Association of External Quality Assessment Service. We performed a pilot project of anti-D titer test for the expansion of proficiency testing program in transfusion medicine.
Methods: Proficiency testing materials with low (BBS2-21-01) and high (BBS2-21-02) anti-D titer were sent to 53 laboratories that agreed to participate in the pilot project for the 2nd Korean Association of External Quality Assessment Service on Transfusion Medicine in 2021. The results were entered on the website of the Korean Association of External Quality Assessment Service (http://eqas.keqas.org/).
Results: A total of 47 laboratories submitted the results. For BBS2-21-01, the intended response of anti-D titer was 4–16 for tube technique with antihuman globulin (AHG) and 16–64 for column agglutination technique (CAT) with AHG. Meanwhile, for BBS2-21-02, the intended response was 8–32 for tube technique with AHG and 32–128 for CAT with AHG. The proportion of acceptable results was 90.9%–95.5% for tube technique with AHG and 95.8%–100.0% for CAT with AHG.
Conclusions: The pilot project of anti-D titer test was successfully performed. This project will be expanded to a biannual proficiency testing program for anti-D antibody titer in the Korean Association of External Quality Assessment Service starting in 2022.

Keywords: External quality assessment, Transfusion medicine, Anti-D test

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